A.C. is a 60-year-old Caucasian woman with newly diagnosed pepticulcer disease, generalized anxiety disorder, and iron deficiency anemia. She also

  

A.C. is a 60-year-old Caucasian woman with newly diagnosed pepticulcer disease, generalized anxiety disorder, and iron deficiency anemia. She also has a long history of asthma and depression. She is a strong believer of herbal medicine. She takes St. John’s wort for her depression, iron pills for her anemia, and alprazolam (Xanax) as needed for her anxiety. During her asthma exacerbation, she is instructed to take prednisone for at least 5 days. She also takes esomeprazole (Nexium) for her peptic ulcer disease. Three months later, she experienced severe fatigue, shortness of breath, dizziness, and swelling/soreness in the tongue. Her asthma is well controlled with the occasional use of albuterol (Proventil) inhaler. During her physical exam, her physician suspected that she had bacterial vaginosis and gave her a prescription for a 1-week course of metronidazole (Flagyl). She drinks at least two to three cans of beer per day.Think about the fundamental principles of pharmacology and the mechanisms of action for each medication listed above.  Discuss the potential for interactions that may increase drug availability.  What is the cause of increased drug availability?  Evaluate for interactions that will decrease drug availability.  What is the cause of decreased drug availability?  What recommendations may be made concerning the co-administration of these medications?  What specific education would you provide to this patient about her medications?   -Discuss the potential for interactions that may increase drug availability in this case and provide the rationale for this happening -Discuss the  interactions that will decrease drug availability as well as the rationale for that decreased drug availability -Discuss recommendations that may be made concerning the co-administration of these medications  Health Science Science Nursing NURS N521 Share (0)

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